Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167626 | 0.88 | TRPA1 (0.33) | PDK2KDM4EMAPTHTT | |
| SCHEMBL29167645 | 0.88 | PSEN1 (0.32) | — | |
| SCHEMBL29167679 | 0.87 | SLC6A2 (0.33) | SLC6A2 | |
| SCHEMBL29167680 | 0.86 | KMT2A (0.40) | NPSR1PKMPDK2KDM4EMEN1 | |
| SCHEMBL29167744 | 0.86 | CNR1 (0.35) | PDK2MEN1KMT2A | |
| SCHEMBL29167663 | 0.86 | CYP2D6 (0.32) | KDM4EKMT2ATDP1 | |
| SCHEMBL29167667 | 0.85 | TRPV3 (0.35) | KDM4ENPC1HTTTDP1L3MBTL1 | |
| SCHEMBL29167671 | 0.81 | CASP6 (0.32) | SLC6A2 | |
| SCHEMBL29167583 | 0.81 | KDM4E (0.33) | KDM4EMAPT | |
| SCHEMBL29167659 | 0.80 | L3MBTL1 (0.39) | NPSR1PKMPDK2SLC6A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624029-A | Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine | 赣江中药创新中心 | 2024-03-01 | — | — | CN | disclosed |