Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168241 | 1.00 | PPARG (0.43) | PPARGPPARAMAOBLMNAALDH1A1 | |
| SCHEMBL29168191 | 0.82 | PPARG (0.39) | PPARGPPARAMAOBLMNAALDH1A1 | |
| SCHEMBL14237833 | 0.81 | NPC1 (0.41) | PPARGPPARAMAOBLMNAALDH1A1 | |
| SCHEMBL28487501 | 0.81 | SRR (0.46) | PPARGPPARAFAAHPKM | |
| SCHEMBL14208208 | 0.80 | FAAH (0.43) | PPARGPPARAMAOBALDH1A1FAAH | |
| SCHEMBL28634190 | 0.78 | KMT2A (0.36) | PPARGPPARALMNAALDH1A1AOC3 | |
| SCHEMBL28642291 | 0.78 | PNMT (0.44) | PPARGPPARAMAOBMAOAPOLB | |
| SCHEMBL28642289 | 0.78 | PNMT (0.44) | PPARGPPARAMAOBMAOAPOLB | |
| SCHEMBL29168249 | 0.76 | PPARG (0.47) | PPARGPPARALMNAALDH1A1MAP3K14 | |
| SCHEMBL29168248 | 0.76 | PPARG (0.47) | PPARGPPARALMNAALDH1A1MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |