Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30031328 | 1.00 | SLC2A1 (0.40) | SLC2A1AMY1ADHFRNPC1TSHR | |
| SCHEMBL30031048 | 0.90 | SLC2A1 (0.45) | SLC2A1AMY1ADHFRNPC1TSHR | |
| SCHEMBL29168726 | 0.82 | DHFR (0.43) | SLC2A1AMY1ADHFRNPC1TSHR | |
| SCHEMBL30030889 | 0.82 | DHFR (0.43) | SLC2A1AMY1ADHFRNPC1TSHR | |
| SCHEMBL15877172 | 0.80 | SLC2A1 (0.43) | SLC2A1AMY1ADHFRNPC1HTT | |
| SCHEMBL15877057 | 0.72 | DHPS (0.54) | SLC2A1GAAPOLBKMT2ALMNA | |
| SCHEMBL29168707 | 0.71 | EGFR (0.61) | NPC1TSHREGFRMAPT | |
| SCHEMBL30820387 | 0.71 | EGFR (0.61) | NPC1TSHREGFRMAPT | |
| SCHEMBL30031538 | 0.70 | AMY1A (0.45) | AMY1ADHFRNPC1TSHRRAB9A | |
| SCHEMBL15877070 | 0.70 | MAPT (0.38) | SLC2A1DHFRGAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |