Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 5/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168725 | 0.90 | SLC2A1 (0.40) | SLC2A1NPC1TSHRRAB9AGAA | |
| SCHEMBL30031328 | 0.90 | SLC2A1 (0.40) | SLC2A1NPC1TSHRRAB9AGAA | |
| SCHEMBL30030889 | 0.89 | DHFR (0.43) | SLC2A1NPC1TSHRRAB9AGAA | |
| SCHEMBL29168726 | 0.89 | DHFR (0.43) | SLC2A1NPC1TSHRRAB9AGAA | |
| SCHEMBL15877172 | 0.86 | SLC2A1 (0.43) | SLC2A1NPC1GAADHFREGFR | |
| SCHEMBL15877057 | 0.81 | DHPS (0.54) | SLC2A1GAAEGFRPOLBKMT2A | |
| SCHEMBL30030975 | 0.77 | ADORA2A (0.46) | NPC1RAB9ADHFRKMT2AMEN1 | |
| SCHEMBL30031538 | 0.77 | AMY1A (0.45) | NPC1TSHRRAB9AGAAMGAM | |
| SCHEMBL15877070 | 0.76 | MAPT (0.38) | SLC2A1GAADHFRPOLBKMT2A | |
| SCHEMBL9566435 | 0.76 | MGAM (0.54) | NPC1TSHRRAB9AGAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |