Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25343224 | 0.83 | PRPS1 (0.43) | DYRK1ABRD4STK17BSTK17ACA1 | |
| SCHEMBL30568519 | 0.81 | DRD2 (0.41) | DYRK1ABRD4STK17BSTK17ACA1 | |
| SCHEMBL25344128 | 0.81 | DRD2 (0.41) | DYRK1ABRD4STK17BSTK17ACA1 | |
| SCHEMBL31439941 | 0.80 | MAOA (0.42) | BRD4CA1CA2CA12CA9 | |
| SCHEMBL25341649 | 0.79 | DRD2 (0.46) | BRD4CA1CA2CA12CA9 | |
| SCHEMBL25344077 | 0.78 | SSTR4 (0.42) | CPB2CSNK2A2CSNK2A1 | |
| SCHEMBL31440035 | 0.77 | CAMK2D (0.46) | DYRK1ABRD4STK17BSTK17ADRD2 | |
| SCHEMBL26926764 | 0.75 | BRD4 (0.41) | BRD4CCNCCDK8CA1CA2 | |
| SCHEMBL25344456 | 0.75 | SSTR4 (0.37) | CPB2 | |
| SCHEMBL25342761 | 0.74 | DYRK1A (0.47) | DYRK1ABRD4STK17BSTK17ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148129-A1 | IMIDAZOLE MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-10 | — | — | WO | disclosed |