Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid Butyl Ester SCHEMBL15021138 | 0.94 | ALDH1A1 (0.72) | ALDH1A1TSHRNAAAACHEHCAR2 | |
| 2-Methoxyethanol SCHEMBL2382470 | 0.92 | ALDH1A1 (0.54) | ALDH1A1TSHRACHE | |
| Acetic Acid Pentyl Ester SCHEMBL18393753 | 0.90 | ALDH1A1 (0.71) | ALDH1A1TSHRNAAAEPHX1MEN1 | |
| Acetic Acid Pentyl Ester SCHEMBL28121728 | 0.90 | MEN1 (0.56) | ALDH1A1TSHRNAAAEPHX1MEN1 | |
| Butyl Alcohol SCHEMBL28260804 | 0.89 | ALDH1A1 (0.63) | ALDH1A1TSHRNAAAEPHX1ACHE | |
| Acetic Acid Pentyl Ester SCHEMBL8810314 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRNAAAEPHX1ACHE | |
| Acetic Acid Pentyl Ester SCHEMBL27792614 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRNAAAEPHX1ACHE | |
| Acetic Acid Butyl Ester SCHEMBL28160205 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TSHRNAAAEPHX1ACHE | |
| Hexane SCHEMBL4809269 | 0.87 | ALDH1A1 (0.52) | ALDH1A1TSHRNAAAEPHX1MEN1 | |
| Hexyl Acetate SCHEMBL2764089 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TSHRNAAAEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961250-B2 | Short-acting benzodiazepine salts and their polymorphic forms | PAION UK LIMITED (GB) | 2021-03-30 | — | — | US | disclosed |
| US-20200039990-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| US-10472365-B2 | Short-acting benzodiazepine salts and their polymorphic forms | PAION UK LIMITED (GB) | 2019-11-12 | — | — | US | disclosed |
| US-20180186803-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2018-07-05 | — | — | US | disclosed |
| US-9914738-B2 | Short-acting benzodiazepine salts and their polymorphic forms | PAION UK LIMITED (GB) | 2018-03-13 | — | — | US | disclosed |
| US-20180002338-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2018-01-04 | — | — | US | disclosed |
| EP-2852389-B1 | COMPOSITIONS COMPRISING SHORT-ACTING BENZODIAZEPINES | PAION UK LTD (GB) | 2017-10-18 | — | — | EP | disclosed |
| US-9777007-B2 | Short-acting benzodiazepine salts and their polymorphic forms | PAION UK LIMITED (GB) | 2017-10-03 | — | — | US | disclosed |
| US-20160176881-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2016-06-23 | — | — | US | disclosed |
| US-9193730-B2 | Short-acting benzodiazepine salts and their polymorphic forms | PAION UK LIMITED (GB) | 2015-11-24 | — | — | US | disclosed |
| US-20150148338-A1 | COMPOSITIONS COMPRISING SHORT-ACTING BENZODIAZEPINES | PAION UK LIMITED (GB) | 2015-05-28 | — | — | US | disclosed |
| EP-2852389-A1 | COMPOSITIONS COMPRISING SHORT-ACTING BENZODIAZEPINES | Paion UK Limited (GB) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174883-A1 | COMPOSITIONS COMPRISING SHORT-ACTING BENZODIAZEPINES | PAION UK LIMITED (GB) | 2013-11-28 | — | — | WO | disclosed |
| EP-2081921-B1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LTD (GB) | 2010-09-08 | — | — | EP | disclosed |
| US-20100081647-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK LIMITED (GB) | 2010-04-01 | — | — | US | disclosed |
| EP-2081921-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | PAION UK Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008007071-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | CENES LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148338-A1 | COMPOSITIONS COMPRISING SHORT-ACTING BENZODIAZEPINES | GABRA5, GABRA2, GABRA1 | ALDH1A1 951/4885TSHR 1686/4885NAAA 2876/4885 |
| US-20160176881-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-10472365-B2 | Short-acting benzodiazepine salts and their polymorphic forms | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-20180186803-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-20100081647-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-20200039990-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-10961250-B2 | Short-acting benzodiazepine salts and their polymorphic forms | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
| US-20180002338-A1 | SHORT-ACTING BENZODIAZEPINE SALTS AND THEIR POLYMORPHIC FORMS | GABRA5, GABRA6, GABRA1 | ALDH1A1 646/4885TSHR 1325/4885NAAA 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.