Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | C1R | P00736 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546147 | 0.68 | ALDH1A1 (0.32) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL14698522 | 0.64 | MAOA (0.40) | DDR1KDM4EC1RNOTUM | |
| SCHEMBL23689986 | 0.63 | DDR1 (0.40) | DDR1KDM4EMAPTLMNA | |
| SCHEMBL18035349 | 0.62 | JAK2 (0.46) | DDR1ALDH1A1CYP3A4HPGDTDP1 | |
| SCHEMBL5600046 | 0.62 | ALDH1A1 (0.43) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL981089 | 0.61 | ALDH1A1 (0.46) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL533215 | 0.60 | MCL1 (0.39) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL668872 | 0.59 | PDE2A (0.41) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL22366856 | 0.59 | GABRB3 (0.44) | ALDH1A1CYP3A4HPGDALOX15TSHR | |
| SCHEMBL15850522 | 0.59 | PDE2A (0.41) | ALDH1A1CYP3A4HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |