SCHEMBL981089

SCHEMBL981089

FC(F)(F)c1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
CYP3A4 P08684 3/20 0.46
HPGD P15428 2/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
HIF1A Q16665 1/20 0.46
TXNRD1 Q16881 1/20 0.46
TXNRD3 Q86VQ6 1/20 0.46
TXNRD2 Q9NNW7 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PDE2A O00408 1/20 0.42
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GPR35 Q9HC97 2/20 0.41
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
GABRB3 P28472 6/20 0.40
GABRA2 P47869 5/20 0.40
GABRB2 P47870 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3300842 0.85 ALDH1A1 (0.41) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL6222180 0.85 NOTUM (0.43) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL13550111 0.85 RAPGEF4 (0.44) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL31304780 0.83 PTPN5 (0.42) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL1769094 0.83 PTPN5 (0.42) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL15850522 0.80 PDE2A (0.41) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL22366856 0.80 GABRB3 (0.44) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL668872 0.80 PDE2A (0.41) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL25374080 0.78 PDE2A (0.39) ALDH1A1CYP3A4HPGDALOX15TSHR
SCHEMBL5600046 0.78 ALDH1A1 (0.43) ALDH1A1CYP3A4HPGDALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222566829-U 3,4, 5-Trichlorobenzotrifluoride flash distillation device 江西巍华化学有限公司 2025-03-07 CN claimed
CN-119161253-A Method for simultaneously preparing 2, 6-dichloro-4-trifluoromethyl aniline and m-trifluoromethyl aniline 湖北丰山新材料科技有限公司 2024-12-20 CN claimed
CN-221982402-U 3,4, 5-Trichlorobenzotrifluoride neutralization reaction kettle 山东德澳精细化学品有限公司 2024-11-12 CN claimed
CN-116288776-A Anti-aging ultra-high molecular weight polyethylene fiber material and preparation method thereof 中科智汇中小企业服务中心(山东)有限公司 2023-06-23 CN claimed
CN-116008331-A Method for measuring content of liquid electrolyte component of battery 清华大学 2023-04-25 CN claimed
CN-214913466-U 3,4, 5-trichlorobenzotrifluoride flash distillation device 山东德澳精细化学品有限公司 2021-11-30 CN claimed
CN-214916058-U 3,4, 5-trichloro-benzotrifluoride fluorination reaction device 山东德澳精细化学品有限公司 2021-11-30 CN claimed
CN-214916059-U 3,4, 5-trichlorobenzotrifluoride chlorination reaction device 山东德澳精细化学品有限公司 2021-11-30 CN claimed
CN-214916066-U 3,4, 5-trichlorobenzotrifluoride neutralization reaction device 山东德澳精细化学品有限公司 2021-11-30 CN claimed
CN-214914760-U A hydrogen chloride tail gas processing apparatus for 3,4, 5-trichlorobenzotrifluoride is synthetic 山东德澳精细化学品有限公司 2021-11-30 CN claimed
WO-1995000438-A1 METHOD FOR SEPARATING CHLORINE FROM A MIXTURE OF GASES OCCIDENTAL CHEMICAL CORPORATION (US) 1995-01-05 WO claimed
US-5308383-A Absorption by a liquid containing a chlorinated benzotrifluoride OCCIDENTAL CHEMICAL CORPORATION (US) 1994-05-03 US claimed
EP-0354444-B1 PROCESS FOR THE INTRODUCTION OF FLUORINE ON AROMATIC NUCLEUS BY NUCLEOPHILIC EXCHANGE BAYER AG (DE) 1993-01-20 EP claimed
US-4978769-A USING POTASSIUM FLUORIDE, PHASE TRANSFER CATALYSTS, METAL SALTS BAYER AKTIENGESELLSCHAFT (DE) 1990-12-18 US claimed
US-4780559-A Process for preparing organic fluorides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-10-25 US claimed
EP-0034402-B1 METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-08-29 EP claimed
US-4384135-A REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1983-05-17 US claimed
EP-0053321-A2 Substituted derivatives of phenoxy cinnamic acid, process for their preparation and their use as herbicides BAYER AG (DE) 1982-06-09 EP claimed
EP-0034402-A2 Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-26 EP claimed
US-4264769-A BY REACTING A DIHYDROXYBENZENE WITH A HETEROCYCLIC OR PHENYL HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-28 US claimed