Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277970 | 0.82 | ITGB1 (0.40) | ITGB1ITGA5TSHRALDH1A1HSD17B10 | |
| SCHEMBL410165 | 0.78 | ALPL (0.45) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL13893513 | 0.78 | KDM4E (0.41) | ITGB1ITGA5ALDH1A1HSD17B10LMNA | |
| SCHEMBL30954399 | 0.78 | CES2 (0.43) | LMNAMAPTHPGDSMN1; SMN2POLB | |
| SCHEMBL6580698 | 0.77 | ITGB1 (0.38) | ITGB1ITGA5TSHRALDH1A1HSD17B10 | |
| SCHEMBL3775895 | 0.77 | ALDH1A1 (0.47) | ITGB1ITGA5TSHRALDH1A1HSD17B10 | |
| SCHEMBL27617052 | 0.76 | HPGD (0.48) | TSHRLMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8138598 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL30753199 | 0.75 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2POLBAPEX1 | |
| SCHEMBL13390 | 0.75 | TSHR (0.43) | TSHRALDH1A1SMN1; SMN2POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603048-A | Preparation method of ethyl 2,4, 5-trifluorobenzoyl acetate | 安徽森吉制药有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117486706-B | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117486706-A | Synthesis method of 2,4, 5-trifluoro phenylacetic acid | 山东国邦药业有限公司 | 2024-02-02 | — | — | CN | disclosed |