SCHEMBL30954399

SCHEMBL30954399

O=C(OO)c1cc(F)c(F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CES2 O00748 6/20 0.43
CES1 P23141 6/20 0.43
DGAT1 O75907 1/20 0.38
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA4 P22748 2/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
RAB9A P51151 2/20 0.33
GAA P10253 1/20 0.33
ALPL P05186 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410165 0.81 ALPL (0.45) CA1CA2LMNAMAPTHPGD
SCHEMBL29185115 0.78 CES2 (0.33) CES2CES1DGAT1CYP11B1CYP11B2
SCHEMBL29185124 0.78 ITGB1 (0.41) CES2CES1CYP11B1CYP11B2LMNA
SCHEMBL2323641 0.77 DGAT1 (0.54) CES2CES1DGAT1CYP11B1CYP11B2
SCHEMBL30954392 0.76 CES2 (0.68) CES2CES1DGAT1MAPTPOLB
SCHEMBL364791 0.76 POLB (0.40) CA1CA2LMNAMAPTHPGD
SCHEMBL364335 0.76 TSHR (0.53) CA1CA2LMNAMAPTPOLB
SCHEMBL8064572 0.76 CES2 (0.54) CES2CES1DGAT1CYP11B1CYP11B2
SCHEMBL13291389 0.76 CES2 (0.42) CES2CES1DGAT1CYP11B1CYP11B2
SCHEMBL11331912 0.75 CES2 (0.35) CES2CES1DGAT1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634196-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES Momentive Performance Materials GmbH (DE) 2025-10-22 EP disclosed
WO-2024126692-A1 PERACID PROMOTERS IN THE IRIDIUM-CATALYZED HYDROSILYLATION SYNTHESIS OF HALOALKYLORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2024-06-20 WO disclosed