Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415090 | 1.00 | NPC1 (0.37) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2800972 | 0.82 | ALDH1A1 (0.51) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL7729357 | 0.75 | NPC1 (0.59) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7725034 | 0.71 | MAP4K4 (0.41) | NPC1RAB9AKDM4EALDH1A1POLB | |
| SCHEMBL564030 | 0.71 | CASP7 (0.50) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29188907 | 0.70 | NPC1 (0.35) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13297698 | 0.69 | KDM6B (0.47) | NPC1KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1531808 | 0.69 | ALOX15 (0.59) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10739420 | 0.69 | CA1 (0.38) | NPC1RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL12894636 | 0.69 | RAB9A (0.49) | NPC1RAB9AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820250-A | Application of 2-amino-3- (5-mercapto-1, 3, 4-oxadiazole) phenol derivative in osteoporosis | 山东第一医科大学第一附属医院(山东省千佛山医院) | 2024-04-05 | — | — | CN | claimed |
| CN-117820250-A | Application of 2-amino-3- (5-mercapto-1, 3, 4-oxadiazole) phenol derivative in osteoporosis | 山东第一医科大学第一附属医院(山东省千佛山医院) | 2024-04-05 | — | — | CN | disclosed |
| CN-117820250-A | Application of 2-amino-3- (5-mercapto-1, 3, 4-oxadiazole) phenol derivative in osteoporosis | 山东第一医科大学第一附属医院(山东省千佛山医院) | 2024-04-05 | — | — | CN | disclosed |
| CN-117820250-A | Application of 2-amino-3- (5-mercapto-1, 3, 4-oxadiazole) phenol derivative in osteoporosis | 山东第一医科大学第一附属医院(山东省千佛山医院) | 2024-04-05 | — | — | CN | disclosed |