Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | KAT7 | O95251 | 18/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 18/20 | 0.35 |
| ▸ | KAT6B | Q8WYB5 | 13/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 11/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564685 | 0.75 | PDE4B (0.45) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL30019841 | 0.75 | PDE4B (0.45) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL30020086 | 0.67 | KAT7 (0.39) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL25564680 | 0.67 | KAT7 (0.46) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL25561771 | 0.67 | KAT7 (0.70) | KAT7KAT6AKAT6BKAT5KAT8 | |
| SCHEMBL28853149 | 0.62 | ADRB2 (0.54) | PDE4BKAT7KAT6AKAT6B | |
| SCHEMBL28115606 | 0.62 | KAT7 (0.43) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL197433 | 0.61 | CCR1 (0.50) | PDE4B | |
| SCHEMBL29008820 | 0.61 | KDM4E (0.52) | PDE4BKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL10053919 | 0.61 | MEN1 (0.50) | PDE4BKAT7KAT6AKAT6BKAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881677-A | Fused isoxazolyl compounds as KAT6Aw inhibitors | 奥瑞基尼肿瘤有限公司 | 2024-04-12 | — | — | CN | disclosed |