Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150057 | 0.84 | NOTUM (0.40) | MAPK1NPSR1KMT2APOLBMEN1 | |
| SCHEMBL187734 | 0.84 | ALDH1A1 (0.44) | MAPK1KMT2APOLBMAPTNPC1 | |
| SCHEMBL26140305 | 0.79 | NPSR1 (0.50) | LCKMAPK1CA12CA1CA2 | |
| SCHEMBL5117547 | 0.76 | CNR2 (0.40) | NPSR1KMT2APOLBMEN1MAPT | |
| SCHEMBL31489882 | 0.76 | TXNRD1 (0.45) | MAPK1NPSR1KMT2APOLBMEN1 | |
| SCHEMBL25320720 | 0.75 | SIRT6 (0.43) | MAPK1NPSR1KMT2APOLBMEN1 | |
| SCHEMBL31413102 | 0.75 | SIRT6 (0.43) | MAPK1NPSR1KMT2APOLBMEN1 | |
| SCHEMBL11388218 | 0.75 | ALDH1A1 (0.42) | MAPK1NPSR1KMT2APOLBMEN1 | |
| SCHEMBL16372000 | 0.75 | LCK (0.47) | LCKMAPK1CA12CA1CA2 | |
| SCHEMBL30663244 | 0.75 | ALDH1A1 (0.54) | KMT2APOLBMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |