Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 16/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29888663 | 0.81 | CTSB (0.41) | TXNRD1MAPTRAB9AHSP90AA1HTT | |
| SCHEMBL20503680 | 0.79 | GAA (0.37) | TXNRD1S1PR4MAPTMAPK1RAB9A | |
| SCHEMBL3772642 | 0.79 | HTT (0.46) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL29888518 | 0.77 | GPR119 (0.35) | TXNRD1MAPK1HSP90AA1 | |
| SCHEMBL29830024 | 0.76 | TXNRD1 (0.58) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL1848090 | 0.76 | TXNRD1 (0.58) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL29189923 | 0.76 | LCK (0.43) | MAPTMAPK1NPSR1RAB9AMEN1 | |
| SCHEMBL1809848 | 0.76 | SMN1; SMN2 (0.37) | MAPTMAPK1RAB9AHSP90AA1HTT | |
| SCHEMBL187124 | 0.76 | CTSB (0.56) | S1PR4MAPTNPSR1RAB9AHTT | |
| SCHEMBL31121580 | 0.76 | CTSB (0.56) | S1PR4MAPTNPSR1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074919-A1 | Heteroaryl compounds as inhibitors of irak4, compositions and applications thereof | ACCRO BIOSCIENCE HK LTD (HK) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074919-A1 | Heteroaryl compounds as inhibitors of irak4, compositions and applications thereof | IRAK4, IRAK1, IRAK2 | TXNRD1 2083/4885S1PR4 1670/4885MAPT 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.