Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881538 | 0.81 | ALDH1A1 (0.50) | ALDH1A1IDO1MEN1KMT2ASCN8A | |
| SCHEMBL6077314 | 0.79 | LMNA (0.53) | IDO1MEN1KMT2AGAATAAR1 | |
| SCHEMBL29196279 | 0.78 | ALDH1A1 (0.47) | ALDH1A1IDO1MEN1KMT2ASCN8A | |
| SCHEMBL29196358 | 0.77 | IDO1 (0.41) | ALDH1A1IDO1MEN1KMT2ASCN8A | |
| SCHEMBL3964858 | 0.75 | ALDH1A1 (0.51) | ALDH1A1IDO1EPHX2PPARGMEN1 | |
| Chloromethane SCHEMBL27446335 | 0.75 | CYP3A4 (0.45) | IDO1EPHX2MEN1KMT2ATP53 | |
| SCHEMBL296280 | 0.74 | ALDH1A1 (0.55) | ALDH1A1IDO1MEN1KMT2ASCN8A | |
| SCHEMBL2178103 | 0.74 | CYP3A4 (0.48) | IDO1EPHX2MEN1KMT2ATP53 | |
| SCHEMBL6921088 | 0.74 | LSS (0.48) | ALDH1A1EPHX2PPARGLSSPPARA | |
| SCHEMBL1436108 | 0.73 | PTPN1 (0.54) | ALDH1A1IDO1MEN1KMT2ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117924277-A | Oxime ether compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-04-26 | — | — | CN | disclosed |