Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CCNK | O75909 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26819168 | 0.90 | KCNH3 (0.44) | KCNH3PTGS1PTGS2CCNKCDK9 | |
| SCHEMBL20814491 | 0.83 | LMNA (0.50) | KCNH3LMNAVCP | |
| SCHEMBL20511448 | 0.81 | PDE4A (0.42) | PTGS2LMNAVCP | |
| SCHEMBL29167207 | 0.79 | KCNH3 (0.54) | KCNH3PTGS1PTGS2CCNKCDK9 | |
| SCHEMBL19461971 | 0.73 | CCNT1 (0.44) | KCNH3CCNKCDK9CCNT1PIM1 | |
| SCHEMBL20511114 | 0.72 | KCNH3 (0.57) | KCNH3ALDH1A1 | |
| SCHEMBL10168927 | 0.72 | KMT2A (0.57) | LMNA | |
| SCHEMBL31229559 | 0.71 | ALDH1A1 (0.40) | KCNH3CCNKCDK9ALDH1A1CCNT1 | |
| SCHEMBL15056480 | 0.71 | CCNK (0.47) | CCNKCDK9CCNT1 | |
| SCHEMBL19462025 | 0.71 | CCNT1 (0.50) | KCNH3CDK9CCNT1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417328-A | Triazine compound for reversing anticoagulant activity of low-molecular heparin, and preparation method and application thereof | 中国药科大学 | 2024-01-19 | — | — | CN | disclosed |