Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501201 | 0.88 | HSD11B1 (0.50) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28516344 | 0.84 | HCAR1 (0.48) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28510485 | 0.78 | HSD11B1 (0.61) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL29198159 | 0.76 | PARP1 (0.42) | GPR119CCR5KDM4EMAPTTHRB | |
| SCHEMBL28511175 | 0.76 | CCR5 (0.50) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28505601 | 0.76 | CCR5 (0.50) | GPR119CCR5HCAR1FPR2KDM4E | |
| SCHEMBL31134382 | 0.76 | GPR119 (0.47) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28498684 | 0.76 | CCR5 (0.48) | GPR119PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL29198169 | 0.75 | PARP1 (0.42) | GPR119CCR5KDM4EMAPTTHRB | |
| SCHEMBL3246870 | 0.75 | OPRM1 (0.55) | GPR119PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074511-B | Substituted benzodiazoles and their use in therapy | 托马斯·黑勒戴药物研究基金会 | 2024-04-26 | — | — | CN | disclosed |