Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670784 | 0.98 | SIGMAR1 (0.53) | SIGMAR1DNM1L3MBTL1MAOA | |
| Hydrochloric Acid SCHEMBL10607355 | 0.96 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2AKDM4EAPEX1 | |
| Iodide SCHEMBL9672333 | 0.96 | SIGMAR1 (0.52) | SIGMAR1DNM1L3MBTL1MAOA | |
| Hydrochloric Acid SCHEMBL10426027 | 0.96 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2AKDM4EAPEX1 | |
| Hydrochloric Acid SCHEMBL11703699 | 0.96 | SIGMAR1 (0.52) | SIGMAR1MEN1KMT2AKDM4EAPEX1 | |
| SCHEMBL11134605 | 0.96 | MAOA (0.52) | SIGMAR1KDM4EL3MBTL1MAOA | |
| Hydrochloric Acid SCHEMBL28728354 | 0.94 | KDM4E (0.52) | SIGMAR1MEN1KMT2AKDM4ESMN1; SMN2 | |
| Iodide SCHEMBL9670517 | 0.94 | CHRM2 (0.51) | SIGMAR1KDM4EL3MBTL1MAOA | |
| Bromide SCHEMBL16742456 | 0.91 | DNM1 (0.60) | MEN1KMT2ASMN1; SMN2DNM1 | |
| Hydrochloric Acid SCHEMBL11805981 | 0.90 | MEN1 (0.54) | SIGMAR1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118718910-A | Microcapsule of silica coated high molecular polymer and preparation method thereof | 常州大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-113636561-B | Carbon-coated hollow silicon material, and preparation method and application thereof | 中国恩菲工程技术有限公司 | 2024-04-26 | — | — | CN | disclosed |