Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185674 | 0.84 | TSHR (0.53) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL12816300 | 0.82 | LMNA (0.36) | TSHRLMNAALDH1A1HPGD | |
| SCHEMBL9149994 | 0.81 | CALM1 (0.35) | TSHRLMNAALDH1A1CYP1A2IDO1 | |
| SCHEMBL12814562 | 0.78 | ACHE (0.39) | TSHRLMNAALDH1A1CYP1A2IDO1 | |
| SCHEMBL12817172 | 0.75 | FTO (0.33) | TSHRLMNAALDH1A1HPGD | |
| SCHEMBL12816351 | 0.74 | RAPGEF4 (0.35) | TSHRLMNAALDH1A1CYP1A2 | |
| SCHEMBL12817242 | 0.73 | HDAC4 (0.35) | ALDH1A1CYP1A2PNMTHPGDRXRA | |
| SCHEMBL12817381 | 0.73 | ACHE (0.40) | TSHRLMNAALDH1A1CYP1A2 | |
| SCHEMBL12815749 | 0.73 | TP53 (0.37) | TSHRLMNACYP2A6ALDH1A1CYP1A2 | |
| SCHEMBL12818305 | 0.72 | LMNA (0.31) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117660992-A | Synthesis method of organosilicon compound containing Si-O bond | 新疆大学 | 2024-03-08 | — | — | CN | disclosed |