Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665309 | 0.83 | ALDH1A1 (0.62) | KCNA3SERPINE1TMPRSS4MAPTPTGDR2 | |
| SCHEMBL17277091 | 0.81 | MAP2 (0.48) | SERPINE1SLC6A4SLC6A3TMPRSS4HSD17B3 | |
| SCHEMBL3223294 | 0.80 | CHRNB2 (0.65) | — | |
| SCHEMBL4280740 | 0.80 | FOLH1 (0.59) | SERPINE1PTGDR2 | |
| SCHEMBL29201441 | 0.78 | KCNA3 (0.49) | KCNA3CHEK1RETPDGFRBPIM1 | |
| SCHEMBL3787454 | 0.78 | ALDH1A1 (0.50) | TMPRSS4MAPT | |
| SCHEMBL4030359 | 0.77 | BCAT2 (0.63) | CNR1MAPTPTGDR2 | |
| SCHEMBL7987535 | 0.77 | ALDH1A1 (0.67) | — | |
| SCHEMBL5858446 | 0.75 | ALDH1A1 (0.51) | PDK2MAPT | |
| SCHEMBL824657 | 0.75 | JAK2 (0.49) | SLC6A4SLC6A3TMPRSS4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835599-B | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-114835599-A | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2022-08-02 | — | — | CN | disclosed |