Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 7/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30992201 | 0.83 | FOLH1 (0.53) | MCL1 | |
| SCHEMBL29971164 | 0.82 | CHRNB2 (0.45) | KCNA3PLK1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL20814166 | 0.78 | MCL1 (0.47) | PLK1MCL1GAA | |
| SCHEMBL29201416 | 0.78 | KCNA3 (0.53) | KCNA3CHEK1RETPDGFRBPIM1 | |
| SCHEMBL3223294 | 0.76 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4FGFR1 | |
| SCHEMBL27912384 | 0.73 | MCL1 (0.44) | MCL1HDAC7 | |
| SCHEMBL17201241 | 0.72 | GAA (0.51) | PLK1MCL1GAA | |
| SCHEMBL3757526 | 0.71 | ALDH1A1 (0.48) | MCL1 | |
| SCHEMBL8758668 | 0.71 | ESR2 (0.53) | — | |
| SCHEMBL30309544 | 0.70 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114835599-B | Preparation method of o-aryl benzamide compound | 绍兴久孚新材料科技有限公司 | 2024-05-03 | — | — | CN | disclosed |