Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616319 | 0.83 | ALPL (0.39) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL29201443 | 0.77 | HPGD (0.36) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL27712665 | 0.76 | CHRNB2 (0.46) | KMT2A | |
| SCHEMBL28745298 | 0.75 | ALPI (0.40) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL28453341 | 0.75 | EPAS1 (0.38) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL576200 | 0.74 | MMP2 (0.55) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL28745391 | 0.72 | ALPI (0.42) | ALPI | |
| SCHEMBL22468700 | 0.72 | MMP2 (0.33) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL28825688 | 0.71 | SLC22A12 (0.36) | CA2CA1CA9 | |
| SCHEMBL20508397 | 0.71 | MMP2 (0.33) | MMP2MMP9MMP14MMP7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729921-A | Compounds and methods as PD1/PD-L1 inhibitors | 朱比兰特普罗德尔有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117295717-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |