Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242246 | 0.74 | LMNA (0.47) | ALDH1A1HTTKDM4EMAPTCA2 | |
| SCHEMBL28226295 | 0.73 | — | — | |
| SCHEMBL1605236 | 0.73 | EPAS1 (0.40) | — | |
| SCHEMBL6942049 | 0.71 | HTT (0.49) | HPGDALDH1A1HTTMMP1MMP2 | |
| SCHEMBL575589 | 0.71 | CA2 (0.52) | HPGDALDH1A1MMP1MMP2MMP7 | |
| SCHEMBL927493 | 0.71 | ALDH1A1 (0.45) | HPGDALDH1A1MMP1MMP2MMP7 | |
| SCHEMBL27616319 | 0.70 | ALPL (0.39) | HPGDALDH1A1HTTMMP2MMP7 | |
| SCHEMBL17426927 | 0.68 | KCNH2 (0.39) | HPGDALDH1A1MMP1MMP2MMP7 | |
| SCHEMBL12656068 | 0.67 | ENPP2 (0.39) | HCAR2 | |
| SCHEMBL3250839 | 0.67 | KDM4E (0.34) | ALDH1A1MMP9KDM4ECA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729921-A | Compounds and methods as PD1/PD-L1 inhibitors | 朱比兰特普罗德尔有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117295717-A | LPA receptor antagonists and uses thereof | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |