Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | FOS | P01100 | 2/20 | 0.31 |
| ▸ | JUN | P05412 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.31 |
| ▸ | RELA | Q04206 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291068 | 0.79 | CA1 (0.35) | CA2CA1CA9 | |
| SCHEMBL28825630 | 0.78 | MMP2 (0.42) | MMP2MMP9MMP14MMP7CA2 | |
| SCHEMBL28745298 | 0.76 | ALPI (0.40) | MMP2MMP9MMP14MMP7POLB | |
| SCHEMBL22468700 | 0.73 | MMP2 (0.33) | MMP2MMP9MMP14MMP7POLB | |
| SCHEMBL28823727 | 0.71 | NFE2L2 (0.44) | MMP2MMP9MMP14MMP7YAP1 | |
| SCHEMBL3713538 | 0.71 | CHRNB2 (0.39) | MMP2MMP9MMP14MMP7YAP1 | |
| SCHEMBL28825688 | 0.71 | SLC22A12 (0.36) | POLBCA2CA1CA9 | |
| SCHEMBL29201426 | 0.71 | MMP2 (0.37) | MMP2MMP9MMP14MMP7YAP1 | |
| SCHEMBL15453567 | 0.70 | CA2 (0.61) | MMP2MMP9MMP14MMP7YAP1 | |
| SCHEMBL15453762 | 0.70 | SOD1 (0.39) | MMP2MMP9MMP14MMP7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349761-B1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2022-01-26 | — | — | EP | disclosed |
| US-10392379-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180273520-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Bioscience, Inc. (US) | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392379-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | MMP2 3991/4885MMP9 4608/4885MMP14 4469/4885 |
| US-20180273520-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | MMP2 3991/4885MMP9 4608/4885MMP14 4469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.