Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394688 | 0.78 | KDM4E (0.59) | KMT2AMEN1NPC1RAB9AHCRTR1 | |
| SCHEMBL18502795 | 0.73 | KDM4E (0.45) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL29282173 | 0.73 | MEN1 (0.68) | KMT2AMEN1RAB9AHCRTR1KDM4E | |
| SCHEMBL14931058 | 0.72 | ALKBH5 (0.72) | KMT2AMEN1NPC1RAB9AHCRTR1 | |
| SCHEMBL291182 | 0.71 | ALDH1A1 (0.60) | KMT2ANPC1RAB9AKDM4EPDE2A | |
| SCHEMBL29376451 | 0.71 | ALDH1A1 (0.60) | KMT2ANPC1RAB9AKDM4EPDE2A | |
| SCHEMBL29202682 | 0.70 | MEN1 (0.56) | KMT2AMEN1HCRTR1KDM4ERXFP1 | |
| SCHEMBL30888893 | 0.70 | MEN1 (0.56) | KMT2AMEN1HCRTR1KDM4ERXFP1 | |
| SCHEMBL29282175 | 0.70 | ALKBH5 (0.50) | KMT2AMEN1NPC1RAB9AHCRTR1 | |
| Hydrochloric Acid SCHEMBL28881738 | 0.70 | ALDH1A1 (0.58) | KMT2ANPC1RAB9AKDM4EPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946104-A | Preparation method of iodine-mediated indolo [2,3-b ] quinoline compound in water phase | 山东第二医科大学 | 2024-04-30 | — | — | CN | disclosed |