Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | WDR5 | P61964 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.53 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204834 | 0.94 | XPO1 (0.63) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204824 | 0.92 | XPO1 (0.61) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204806 | 0.90 | WDR5 (0.61) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204841 | 0.90 | XPO1 (0.66) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204805 | 0.89 | XPO1 (0.88) | XPO1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL30883146 | 0.89 | XPO1 (0.88) | XPO1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL29204826 | 0.88 | WDR5 (0.57) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204813 | 0.84 | WDR5 (0.57) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL30883139 | 0.83 | XPO1 (0.77) | XPO1KDM4ELMNAMAPTWDR5 | |
| SCHEMBL29204831 | 0.83 | XPO1 (0.77) | XPO1KDM4ELMNAMAPTWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |