Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 4/20 | 0.57 |
| ▸ | XPO1 | O14980 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883141 | 0.92 | XPO1 (0.66) | XPO1HDAC1HDAC8HDAC6MAPK1 | |
| SCHEMBL29204829 | 0.92 | XPO1 (0.66) | XPO1HDAC1HDAC8HDAC6MAPK1 | |
| SCHEMBL29204806 | 0.89 | WDR5 (0.61) | WDR5XPO1MAPK1MEN1KMT2A | |
| SCHEMBL29204810 | 0.88 | XPO1 (0.70) | WDR5XPO1KMT2AALDH1A1RXFP1 | |
| SCHEMBL29204813 | 0.84 | WDR5 (0.57) | WDR5XPO1MAPK1MEN1KMT2A | |
| SCHEMBL29204834 | 0.82 | XPO1 (0.63) | WDR5XPO1KMT2AALDH1A1NPSR1 | |
| SCHEMBL29204824 | 0.81 | XPO1 (0.61) | WDR5XPO1KMT2ALMNAMAPT | |
| SCHEMBL29204841 | 0.79 | XPO1 (0.66) | WDR5XPO1KMT2AALDH1A1LMNA | |
| SCHEMBL8705195 | 0.77 | HTR1D (0.70) | MAPK1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL30883146 | 0.77 | XPO1 (0.88) | XPO1MAPK1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |