Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 5/20 | 0.61 |
| ▸ | XPO1 | O14980 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.52 |
| ▸ | ASH2L | Q9UBL3 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204810 | 0.90 | XPO1 (0.70) | WDR5XPO1ALDH1A1HTTMCL1 | |
| SCHEMBL29204826 | 0.89 | WDR5 (0.57) | WDR5XPO1ALDH1A1RXFP1KDM4E | |
| SCHEMBL29204830 | 0.87 | XPO1 (0.69) | XPO1ALDH1A1HTTMCL1KDM4E | |
| SCHEMBL30883143 | 0.87 | XPO1 (0.69) | XPO1ALDH1A1HTTMCL1KDM4E | |
| SCHEMBL29204813 | 0.85 | WDR5 (0.57) | WDR5XPO1ALDH1A1HTTRXFP1 | |
| SCHEMBL29204834 | 0.84 | XPO1 (0.63) | WDR5XPO1ALDH1A1RXFP1KDM4E | |
| SCHEMBL29204824 | 0.83 | XPO1 (0.61) | WDR5XPO1KDM4EKMT2ARBBP5 | |
| SCHEMBL29204837 | 0.82 | XPO1 (0.65) | WDR5XPO1ALDH1A1HTTRXFP1 | |
| SCHEMBL29204841 | 0.81 | XPO1 (0.66) | WDR5XPO1ALDH1A1KDM4EKMT2A | |
| SCHEMBL30883141 | 0.81 | XPO1 (0.66) | XPO1HTTMCL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964578-A | Non-covalent CRM1 inhibitor and preparation method and application thereof | 四川大学 | 2024-05-03 | — | — | CN | disclosed |