Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 3/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696345 | 0.83 | ACP1 (0.47) | EGFRMAPK10RIPK2FGFR2BMPR2 | |
| SCHEMBL18377063 | 0.81 | TTK (0.51) | MAPK10RIPK2BMPR2CDK4CCND1 | |
| SCHEMBL29368477 | 0.81 | TTK (0.51) | MAPK10RIPK2BMPR2CDK4CCND1 | |
| SCHEMBL18376773 | 0.80 | PTK2 (0.55) | FGFR2SCN9A | |
| SCHEMBL29371922 | 0.78 | ALDH1A1 (0.52) | MAPK10JUNMAPT | |
| SCHEMBL28696348 | 0.78 | ALDH1A1 (0.52) | MAPK10JUNMAPT | |
| SCHEMBL18377040 | 0.76 | PIK3CG (0.60) | EGFRMAPK10RIPK2CDK2JUN | |
| SCHEMBL29370809 | 0.76 | PIK3CG (0.60) | EGFRMAPK10RIPK2CDK2JUN | |
| SCHEMBL5168948 | 0.75 | ALDH1A1 (0.49) | IKBKBCHUKSYK | |
| SCHEMBL18376777 | 0.75 | EGFR (0.60) | EGFRCDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999180-B | Quinazoline compound, intermediate, preparation method, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2024-03-26 | — | — | CN | disclosed |