Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936706 | 0.71 | HRH4 (0.49) | HRH4KMT2AHTR3A | |
| SCHEMBL28767631 | 0.69 | P2RX3 (0.31) | — | |
| SCHEMBL16192149 | 0.66 | CHRM2 (0.31) | — | |
| SCHEMBL24936718 | 0.66 | CA1 (0.38) | HRH4 | |
| SCHEMBL29211469 | 0.65 | — | — | |
| SCHEMBL29011021 | 0.65 | — | — | |
| SCHEMBL24256392 | 0.65 | HTR3A (0.41) | HRH4HTR3A | |
| SCHEMBL28952056 | 0.65 | ALDH1A1 (0.41) | KMT2A | |
| SCHEMBL4472198 | 0.64 | HRH4 (0.43) | HRH4HTTKMT2A | |
| SCHEMBL28106920 | 0.63 | GAA (0.56) | KDM4EPARP1KMT2ACHEK1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999256-A | Protein secretion inhibitor | 分子门生物科技公司 | 2024-05-07 | — | — | CN | disclosed |