Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Eprodisate SCHEMBL29220606 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL918473 | 1.00 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL34216 | 0.96 | APP (0.65) | APPPTGS1PDE4ALMNASLC6A6 | |
| SCHEMBL917843 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL218552 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL23795561 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL2288862 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL2522163 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL23795563 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 | |
| Eprodisate SCHEMBL2519325 | 0.92 | APP (0.61) | APPPTGS1PDE4ALMNASLC6A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720439-A | Preparation method of 1, 3-propanedisulfonyl fluoride | 河北圣泰材料股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| US-20130296434-A1 | FORMULATIONS AND METHODS FOR TREATING AMYLOIDOSIS | KIACTA SARL (CA) | 2013-11-07 | — | — | US | claimed |
| US-8372886-B2 | Treatment of renal disorders, diabetic nephropathy and dyslipidemias | KIACTA SARL (CH) | 2013-02-12 | — | — | US | claimed |
| EP-1968561-B1 | TREATMENT OF DIABETIC NEPHROPATHY | BELLUS HEALTH INT LTD (CH) | 2010-09-15 | — | — | EP | claimed |
| US-20070238788-A1 | Treatment of renal disorders, diabetic nephropathy and dyslipidemias | KIACTA SARL (CH) | 2007-10-11 | — | — | US | claimed |
| US-20060167095-A1 | Method for treating amyloidosis | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2006-07-27 | — | — | US | claimed |
| US-20260103445-A1 | Compositions Comprising a Retinoid X Receptor (RXR) Agonist, a Retinoic Acid Receptor (RAR) Agonist, or a Dual RXR/RAR Agonist | UNIV ARIZONA STATE (US) | 2026-04-16 | — | — | US | disclosed |
| US-12540121-B2 | Compositions comprising a retinoid X receptor (RXR) agonist, a retinoic acid receptor (RAR) agonist, or a dual RXR/RAR agonist | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2026-02-03 | — | — | US | disclosed |
| US-12129239-B2 | Method for producing methylene disulfonate compound | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2024-10-29 | — | — | US | disclosed |
| EP-4006020-B1 | METHOD FOR PRODUCING CYCLIC DISULFONIC ACID ESTER COMPOUND | SUMITOMO SEIKA CHEMICALS (JP) | 2024-09-25 | — | — | EP | disclosed |
| CN-117720439-A | Preparation method of 1, 3-propanedisulfonyl fluoride | 河北圣泰材料股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114144407-B | Process for producing cyclic disulfonate compound | 住友精化株式会社 | 2024-02-13 | — | — | CN | disclosed |
| CN-117210885-A | Electroplating solution for simulating composite current collector water electroplating process and Halin test method | 斯迪克新型材料（江苏）有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-5840294-A | INHIBITING AMYLOID DEPOSITION BY ADMINISTERING A THERAPEUTIC COMPOUND COMPRISING AN ANIONIC GROUP AND A CARRIER MOLECULE | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-11-24 | — | — | US | disclosed |
| US-5728375-A | ADMINISTERING A COMPOUND COMPRISING AN ANIONIC GROUP AND A CARRIER MOLECULE; INHIBITS DEPOSITION BY PREVENTING INTERACTION BETWEEN AN AMYLOIDOGENIC PROTEIN AND A BASEMENT MEMBRANE CONSTITUENT | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-03-17 | — | — | US | disclosed |
| EP-0814842-A1 | METHOD FOR TREATING AMYLOIDOSIS | Queen's University at Kingston (CA) | 1998-01-07 | — | — | EP | disclosed |
| US-5643562-A | ANTIDEPOSIT AGENTS FOR PROTEINS FOR MEDICAL DIAGNOSIS OF DISEASES | QUEEN'S UNIVERSITY OF KINGSTON (CA) | 1997-07-01 | — | — | US | disclosed |
| WO-1996028187-A1 | METHOD FOR TREATING AMYLOIDOSIS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1996-09-19 | — | — | WO | disclosed |
| EP-0691844-A1 | METHOD FOR TREATING AMYLOIDOSIS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022437-A2 | METHOD FOR TREATING AMYLOIDOSIS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1994-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129239-B2 | Method for producing methylene disulfonate compound | TST, MPST, SQOR | APP 4724/4885PTGS1 1297/4885PDE4A 4430/4885 |
| US-20060167095-A1 | Method for treating amyloidosis | TTR, IAPP, APP | APP 3/4885PTGS1 3896/4885PDE4A 4579/4885 |
| US-12540121-B2 | Compositions comprising a retinoid X receptor (RXR) agonist, a retinoic acid receptor (RAR) agonist, or a dual RXR/RAR agonist | RXRA, RXRB, RARA | APP 138/4885PTGS1 4105/4885PDE4A 2375/4885 |
| US-20260103445-A1 | Compositions Comprising a Retinoid X Receptor (RXR) Agonist, a Retinoic Acid Receptor (RAR) Agonist, or a Dual RXR/RAR Agonist | RXRA, RXRG, RXRB | APP 210/4885PTGS1 3882/4885PDE4A 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.