Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 3/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922278 | 0.98 | L3MBTL1 (0.69) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL16807286 | 0.94 | NPSR1 (0.60) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL7560417 | 0.93 | L3MBTL1 (0.66) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL16807279 | 0.88 | HPGD (0.57) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL2528895 | 0.84 | LMNA (0.67) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL1755267 | 0.84 | L3MBTL1 (0.58) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL16781980 | 0.83 | TDP1 (0.62) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL6642403 | 0.83 | NPC1 (0.63) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL1791859 | 0.83 | NPC1 (0.68) | L3MBTL1TDP1CES2CES1NPC1 | |
| SCHEMBL7017619 | 0.83 | ALDH1A1 (0.57) | L3MBTL1TDP1CES2CES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303525-B1 | PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS | EVONIK DEGUSSA GMBH (DE) | 2010-09-08 | — | — | EP | disclosed |