Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.32 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218839 | 0.88 | USP2 (0.44) | USP2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL29218799 | 0.80 | PTGIR (0.49) | ALDH1A1PARP15PARP10PARP2PTGIR | |
| SCHEMBL29218626 | 0.78 | NPC1 (0.34) | USP2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL29218556 | 0.77 | L3MBTL1 (0.49) | ALDH1A1MAPTKMT2A | |
| SCHEMBL29218762 | 0.77 | EPHX1 (0.41) | ALDH1A1MAPTKDM4ELMNACNR2 | |
| SCHEMBL29218546 | 0.76 | PRSS1 (0.39) | MAPTKMT2APRSS1TPSAB1TPSD1 | |
| SCHEMBL25039645 | 0.76 | BTK (0.37) | CNR2CNR1MAPK14 | |
| SCHEMBL29218805 | 0.76 | MAPT (0.37) | ALDH1A1MAPTCNR2CNR1KMT2A | |
| SCHEMBL29218696 | 0.75 | MGLL (0.44) | CNR2 | |
| SCHEMBL111361 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |