Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30892882 | 0.85 | LMNA (0.39) | MAPTLMNAMEN1MAPK1RAB9A | |
| SCHEMBL2472746 | 0.76 | SRC (0.60) | MAPTLMNAMEN1MAPK1RAB9A | |
| SCHEMBL1974047 | 0.76 | TSHR (0.54) | MAPTLMNARAB9ARXFP1BLM | |
| SCHEMBL1902930 | 0.76 | CES2 (0.53) | MAPTLMNAMEN1MAPK1RAB9A | |
| SCHEMBL483025 | 0.75 | SRC (0.58) | — | |
| SCHEMBL11662056 | 0.74 | MAPT (0.37) | MAPTLMNAMEN1MAPK1RAB9A | |
| Ammonia Solution, Strong SCHEMBL11664408 | 0.73 | SRC (0.56) | — | |
| SCHEMBL7270129 | 0.73 | SRC (0.56) | — | |
| SCHEMBL9058387 | 0.73 | MMP2 (0.43) | MAPTLMNAMEN1MAPK1RAB9A | |
| SCHEMBL545148 | 0.70 | CYP3A4 (0.58) | MAPTLMNAMEN1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897484-A | Antisense oligonucleotides and their use for treating neurodegenerative disorders | 卫材R&D管理有限公司 | 2024-04-16 | — | — | CN | disclosed |