Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219085 | 0.85 | MAPT (0.41) | LMNABLMMAPK1RAB9AMEN1 | |
| SCHEMBL28251223 | 0.73 | CYP2A6 (0.38) | LMNAKDM4EMAPK1ALDH1A1RAB9A | |
| SCHEMBL11670609 | 0.70 | ALDH1A1 (0.41) | LMNAKDM4EMAPK1TDP1ALDH1A1 | |
| SCHEMBL11581695 | 0.69 | ALDH1A1 (0.58) | LMNAL3MBTL1KDM4EMAPK1TDP1 | |
| SCHEMBL27977311 | 0.69 | ALDH1A1 (0.44) | LMNAL3MBTL1KDM4EMAPK1TDP1 | |
| SCHEMBL1974047 | 0.69 | TSHR (0.54) | LMNABLMKDM4ETDP1ALDH1A1 | |
| SCHEMBL10665272 | 0.68 | MMP1 (0.51) | KDM4EMAPK1TDP1ALDH1A1PYCR1 | |
| SCHEMBL30592712 | 0.68 | LMNA (0.35) | LMNAL3MBTL1KDM4EMAPK1ALDH1A1 | |
| SCHEMBL28056948 | 0.67 | NPC1 (0.40) | LMNAL3MBTL1KDM4EMAPK1ALDH1A1 | |
| SCHEMBL28032276 | 0.66 | CYP2C19 (0.58) | LMNABLMMAPK1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897484-A | Antisense oligonucleotides and their use for treating neurodegenerative disorders | 卫材R&D管理有限公司 | 2024-04-16 | — | — | CN | disclosed |