SCHEMBL29220658

SCHEMBL29220658

O=C1c2ccccc2C(F)c2cc(F)c(F)c(F)c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.36
MAPK1 P28482 2/20 0.35
CYP1A2 P05177 2/20 0.35
MAOA P21397 3/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP1A1 P04798 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
ACHE P22303 1/20 0.34
MAOB P27338 1/20 0.34
BRCA1 P38398 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28619081 0.78 CA1 (0.40) TTRMAPK1CYP1A2MAOAMEN1
SCHEMBL3417192 0.72 TTR (0.53) TTRMAPK1MAOAMEN1KMT2A
SCHEMBL29285411 0.69 MAPK1 (0.44) MAPK1CYP1A2MAOAMEN1KMT2A
SCHEMBL29797969 0.67 GPR3 (0.46) CYP1A2MEN1KMT2AACHEHTR7
SCHEMBL4359049 0.67 GPR3 (0.46) CYP1A2MEN1KMT2AACHEHTR7
SCHEMBL4011644 0.66 HTR7 (0.30) HTR7HTR2B
SCHEMBL29378153 0.66 TTR (0.50) TTRMAPK1MAOAMEN1KMT2A
SCHEMBL31457 0.66 EDNRB (0.40) MAPK1CYP1A2MAOAMEN1KMT2A
SCHEMBL6650819 0.66 MEN1 (0.55) TTRMAPK1CYP1A2MAOAMEN1
SCHEMBL19926520 0.64 MEN1 (0.42) MAPK1CYP1A2MAOAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063342-A Tetrahalogenated monomer containing Schiff base, self-polymerization microporous polymer and preparation method thereof 吉林大学 2024-05-24 CN disclosed