Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | LITAF | Q99732 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29233306 | 0.80 | PIN1 (0.40) | TNFLITAF | |
| SCHEMBL437559 | 0.73 | HAVCR2 (0.40) | TNFLITAFADORA2AADORA1ALOX5AP | |
| SCHEMBL437620 | 0.73 | ALOX5AP (0.38) | TNFLITAFADORA2AADORA1ALOX5AP | |
| SCHEMBL29828879 | 0.72 | PI4KA (0.42) | TNFLITAFADORA2AADORA1ALOX5AP | |
| SCHEMBL8133730 | 0.69 | ATP4A (0.48) | — | |
| SCHEMBL31179075 | 0.68 | HSP90AA1 (0.51) | ADORA2AADORA1 | |
| SCHEMBL437125 | 0.68 | NR4A2 (0.55) | ADORA2AADORA1MPL | |
| SCHEMBL30242047 | 0.68 | TNF (0.45) | TNFLITAF | |
| SCHEMBL9212223 | 0.66 | LRRK2 (0.46) | — | |
| SCHEMBL23497102 | 0.66 | PDE4A (0.42) | TNFLITAFADORA2AADORA1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867714-B | Pesticidal tricyclic compounds | 巴斯夫欧洲公司 | 2024-06-11 | — | — | CN | disclosed |
| EP-4136086-A1 | TRICYCLIC PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-02-22 | — | — | EP | disclosed |
| CN-115427408-A | Pesticidal tricyclic compounds | 巴斯夫欧洲公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-112867714-A | Pesticidal tricyclic compounds | 巴斯夫欧洲公司 | 2021-05-28 | — | — | CN | disclosed |