Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LITAF | Q99732 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437559 | 0.82 | HAVCR2 (0.40) | ALOX5APFEN1TNFLITAFADORA2A | |
| SCHEMBL435849 | 0.80 | HTR1A (0.44) | MCHR1 | |
| SCHEMBL440370 | 0.77 | PARP1 (0.45) | — | |
| SCHEMBL442133 | 0.76 | BACE1 (0.41) | ADORA1HAVCR2 | |
| SCHEMBL29828879 | 0.75 | PI4KA (0.42) | ALOX5APFEN1TNFLITAFADORA2A | |
| SCHEMBL435823 | 0.74 | PARP1 (0.41) | ALOX5APFEN1HAVCR2 | |
| SCHEMBL29233308 | 0.73 | TNF (0.39) | ALOX5APFEN1TNFLITAFADORA2A | |
| SCHEMBL4657366 | 0.72 | MPL (0.40) | ALOX5APFEN1MPLSCN9AKDM4E | |
| SCHEMBL441951 | 0.71 | HAVCR2 (0.58) | KDM4EHAVCR2IGF1R | |
| SCHEMBL441701 | 0.71 | ALDH1A1 (0.43) | KDM4EHAVCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |