Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.41 |
| ▸ | CCR3 | P51677 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034403 | 1.00 | BACE1 (0.48) | BACE1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL23578399 | 0.84 | BACE1 (0.48) | BACE1MEN1KMT2ALMNAMAPT | |
| SCHEMBL23578402 | 0.84 | BACE1 (0.48) | BACE1MEN1KMT2ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL7986763 | 0.78 | LMNA (0.47) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL3936094 | 0.76 | RAB9A (0.60) | BACE1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7609219 | 0.76 | RAB9A (0.60) | BACE1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL5134084 | 0.76 | BACE1 (0.57) | BACE1MAPTITGA4ITGB7 | |
| SCHEMBL5041194 | 0.76 | BACE1 (0.57) | BACE1MAPTITGA4ITGB7 | |
| SCHEMBL28209573 | 0.76 | LMNA (0.46) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL1595963 | 0.75 | KMT2A (0.56) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114845991-B | Method for synthesizing melphalan | 意迪那有限公司 | 2024-05-07 | — | — | CN | disclosed |