Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.35 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 3/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 2/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236442 | 0.76 | PGK1 (0.36) | PGK1PTPN11IKBKBPTGES | |
| SCHEMBL29236521 | 0.75 | MEN1 (0.40) | MEN1KMT2APGK1HAO1ACACB | |
| SCHEMBL29236520 | 0.73 | CHRNB2 (0.37) | MEN1KMT2ACHRNA3PTPN11IKBKB | |
| SCHEMBL29236681 | 0.73 | MEN1 (0.36) | MEN1KMT2AHAO1KIF11 | |
| SCHEMBL30966827 | 0.72 | CYP3A4 (0.42) | MEN1KMT2APGK1PTPN11IKBKB | |
| SCHEMBL23753577 | 0.71 | MEN1 (0.57) | MEN1KMT2ACHRNA3KIF11MRGPRX4 | |
| SCHEMBL30947447 | 0.71 | POLB (0.52) | MEN1KMT2A | |
| SCHEMBL28890049 | 0.69 | MEN1 (0.53) | MEN1KMT2AKIF11 | |
| SCHEMBL28688992 | 0.69 | MEN1 (0.53) | MEN1KMT2AKIF11 | |
| SCHEMBL5260935 | 0.67 | MEN1 (0.52) | MEN1KMT2ACHRNA3KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |