Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 12/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28087485 | 0.79 | LMNA (0.61) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL28087551 | 0.76 | MEN1 (0.71) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL28650599 | 0.74 | MEN1 (0.66) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL6260303 | 0.71 | LMNA (0.61) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL28087507 | 0.70 | LMNA (0.60) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL30339822 | 0.70 | ALOX12 (0.49) | MEN1KMT2AMAOBSMN1; SMN2KDM4E | |
| SCHEMBL3046337 | 0.68 | MAOB (0.61) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL4077096 | 0.68 | LMNA (0.57) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL28087550 | 0.68 | MAOB (0.61) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL3082095 | 0.67 | MAOB (0.63) | LMNANPC1MAOBACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005590-A | Coumarin Schiff base derivative and preparation method and application thereof | 新疆农业大学 | 2024-05-10 | — | — | CN | disclosed |