Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918938 | 0.90 | CNR1 (0.52) | CNR1CNR2P2RX7NPC1RAB9A | |
| SCHEMBL2926527 | 0.89 | RIPK1 (0.47) | CNR1CNR2P2RX7EPHX1MAPK14 | |
| SCHEMBL2926447 | 0.89 | CTSL (0.46) | CNR1CNR2EPHX2NPC1RAB9A | |
| SCHEMBL2925470 | 0.82 | P2RX7 (0.50) | CNR1CNR2P2RX7KITMAPK14 | |
| SCHEMBL2925886 | 0.81 | TSHR (0.43) | EPHX1MAPK14NPC1HPGDKMT2A | |
| SCHEMBL2926594 | 0.80 | HPGD (0.42) | P2RX7EPHX1NPC1RAB9AHPGD | |
| SCHEMBL2925505 | 0.77 | CNR1 (0.47) | CNR1CNR2P2RX7MAPK14KMT2A | |
| SCHEMBL2926823 | 0.75 | CNR2 (0.45) | CNR1CNR2P2RX7MAPK14RAB9A | |
| SCHEMBL2927664 | 0.72 | CTSL (0.58) | CNR1CNR2P2RX7NPC1RAB9A | |
| SCHEMBL2216452 | 0.71 | MAPK14 (0.51) | KITMAPK14CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-B1 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-09-29 | — | — | EP | claimed |