Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924005 | 0.89 | CNR1 (0.41) | RIPK1CTSLCTSSCTSKHPGD | |
| SCHEMBL2918938 | 0.89 | CNR1 (0.52) | HPGDP2RX7CNR1CNR2MAPK1 | |
| SCHEMBL2926447 | 0.89 | CTSL (0.46) | CTSLCTSSCTSKHPGDCNR1 | |
| SCHEMBL2925886 | 0.87 | TSHR (0.43) | HPGDEPHX1MAPK14MAPK1SMN1; SMN2 | |
| SCHEMBL2926594 | 0.85 | HPGD (0.42) | HPGDEPHX1P2RX7ALDH1A1RAB9A | |
| SCHEMBL2856642 | 0.81 | HPGD (0.63) | RIPK1CTSLCTSSCTSKHPGD | |
| SCHEMBL2861261 | 0.79 | HPGD (0.64) | HPGDMAPK14MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL2852350 | 0.77 | NPC1 (0.53) | HPGDCNR1CNR2MAPK1MAPT | |
| SCHEMBL2925505 | 0.76 | CNR1 (0.47) | MAPK14P2RX7CNR1CNR2MAPT | |
| SCHEMBL2854348 | 0.75 | RAB9A (0.54) | HPGDMAPK1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-B1 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-09-29 | — | — | EP | claimed |