Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2924005 | 0.89 | CNR1 (0.41) | CTSLCTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL2918938 | 0.89 | CNR1 (0.52) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2926527 | 0.89 | RIPK1 (0.47) | CTSLCTSSCTSKALDH1A1NPC1 | |
| SCHEMBL2927664 | 0.83 | CTSL (0.58) | CTSLCTSSCTSKPOLBKMT2A | |
| SCHEMBL2925886 | 0.80 | TSHR (0.43) | POLBKMT2AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL2926594 | 0.79 | HPGD (0.42) | KMT2AALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL2860234 | 0.78 | HPGD (0.54) | POLBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2854531 | 0.76 | LMNA (0.52) | POLBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2854802 | 0.76 | LMNA (0.48) | POLBKMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL2853389 | 0.76 | NPC1 (0.62) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615698-B1 | NEW AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-09-29 | — | — | EP | claimed |