Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734634 | 0.85 | CA4 (0.46) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL2744416 | 0.83 | ORAI1 (0.46) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL29113661 | 0.81 | TRPV6 (0.46) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL3888387 | 0.77 | CA4 (0.50) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL8962832 | 0.76 | ALDH1A1 (0.42) | CA4LTA4HTSHRCA1CA2 | |
| SCHEMBL27413707 | 0.74 | CA4 (0.40) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL14983501 | 0.74 | CA4 (0.58) | CA4LTA4HCA1CA2CA7 | |
| SCHEMBL1400376 | 0.74 | MAOA (0.56) | CA4TSHRCA1CA2 | |
| SCHEMBL10389747 | 0.73 | LTA4H (0.41) | CA4ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL14983380 | 0.73 | CA1 (0.48) | CA4LTA4HTSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120114470-A | Pharmaceutical composition for inhibiting NFKBIZ gene expression and application | 张川 | 2025-06-10 | — | — | CN | disclosed |
| CN-118767151-A | Pharmaceutical composition for inhibiting TGFBI gene expression and application thereof | 上海交通大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-118059118-A | Pharmaceutical composition for inhibiting NFKBIZ gene expression and application | 上海交通大学 | 2024-05-24 | — | — | CN | disclosed |