Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.56 |
| ▸ | SRC | P12931 | 3/20 | 0.56 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761686 | 0.85 | EGFR (0.64) | EGFRSRCKDM4EALDH1A1MAPK1 | |
| SCHEMBL29246343 | 0.84 | KDM4E (0.55) | EGFRHTR6KDM4ELMNAHTR1A | |
| SCHEMBL29246503 | 0.83 | HTR6 (0.45) | HTR6KDM4ELMNAHTR1ADRD2 | |
| SCHEMBL29246342 | 0.80 | KDM4E (0.46) | HTR6KDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL7127236 | 0.77 | EGFR (0.71) | EGFRSRCHTR6KDM4EALDH1A1 | |
| SCHEMBL29246399 | 0.75 | ALDH1A1 (0.46) | HTR6KDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL20037062 | 0.73 | ALDH1A1 (0.59) | EGFRSRCHTR6KDM4ELMNA | |
| SCHEMBL27478799 | 0.73 | EGFR (0.69) | EGFRSRCHTR6KDM4EALDH1A1 | |
| SCHEMBL9811674 | 0.72 | KDM4E (0.58) | EGFRHTR6KDM4ELMNAHTR1A | |
| SCHEMBL5268569 | 0.72 | HTR6 (0.70) | EGFRSRCHTR6KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | disclosed |