Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9811674 | 0.89 | KDM4E (0.58) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL29246342 | 0.86 | KDM4E (0.46) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL29246362 | 0.84 | EGFR (0.56) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL29246503 | 0.82 | HTR6 (0.45) | KDM4ELMNAALDH1A1HPGDHTR6 | |
| SCHEMBL29246399 | 0.79 | ALDH1A1 (0.46) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL1165573 | 0.79 | KDM4E (0.68) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL31487317 | 0.79 | KDM4E (0.68) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL5198795 | 0.78 | KDM4E (0.64) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL9536890 | 0.77 | LMNA (0.62) | KDM4ELMNAPKMALDH1A1HSD17B10 | |
| SCHEMBL4438241 | 0.77 | KDM4E (0.62) | KDM4ELMNAPKMALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | disclosed |