Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246362 | 0.83 | EGFR (0.56) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL29246343 | 0.82 | KDM4E (0.55) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL29246342 | 0.80 | KDM4E (0.46) | HTR6KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27817269 | 0.78 | ALDH1A1 (0.60) | HTR6RAD52HTR1ADRD2DRD4 | |
| SCHEMBL29246399 | 0.76 | ALDH1A1 (0.46) | HTR6KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL27780700 | 0.73 | KDM4E (0.44) | RAD52KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL14560403 | 0.72 | RAD52 (0.48) | HTR6RAD52HTR1ADRD2DRD4 | |
| Carbazole SCHEMBL27468925 | 0.71 | KDM4E (0.63) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL9811674 | 0.71 | KDM4E (0.58) | HTR6HTR1ADRD2DRD4HTR1D | |
| SCHEMBL13962342 | 0.70 | SIRT1 (0.48) | HTR6RAD52MCL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307461-A | Preparation method of light-induced palladium-catalyzed difluoro methylene indole compound | 大连理工大学 | 2024-07-09 | — | — | CN | disclosed |