Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249095 | 0.86 | MEN1 (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29249036 | 0.86 | MEN1 (0.48) | MEN1KMT2AKDM4EALOX5SMN1; SMN2 | |
| SCHEMBL29249050 | 0.84 | KMT2A (0.53) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL29249055 | 0.84 | MEN1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL5014974 | 0.81 | PDE1A (0.52) | MEN1KMT2AKDM4EALDH1A1ACHE | |
| SCHEMBL7274477 | 0.81 | ACHE (0.43) | MEN1KMT2AACHE | |
| SCHEMBL29249101 | 0.81 | ALOX5 (0.56) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8132968 | 0.77 | MEN1 (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29249069 | 0.76 | KMT2A (0.51) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7283362 | 0.76 | L3MBTL1 (0.45) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290433-A | Preparation method and application of chiral dihydrofuran [3,4-b ] quinoline-1 (3H) -ketone | 南开大学 | 2024-07-05 | — | — | CN | disclosed |