Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 2/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20788983 | 0.85 | PDE3B (0.63) | PDE1APDE1BPDE3BPDE1CPDE3A | |
| SCHEMBL5015003 | 0.81 | PDE1A (0.53) | PDE1APDE1BPDE3BPDE1CPDE3A | |
| SCHEMBL29249103 | 0.81 | ESR1 (0.52) | MEN1KMT2AACHEKDM4EALOX5 | |
| SCHEMBL8133213 | 0.75 | PDE3B (0.50) | PDE1APDE1BPDE3BPDE1CPDE3A | |
| SCHEMBL8132968 | 0.75 | MEN1 (0.53) | PDE1APDE1BPDE3BPDE1CPDE3A | |
| SCHEMBL7274477 | 0.74 | ACHE (0.43) | MEN1KMT2ABCHEACHE | |
| SCHEMBL29249101 | 0.74 | ALOX5 (0.56) | MEN1KMT2ACYP19A1TP53TSHR | |
| SCHEMBL29249095 | 0.71 | MEN1 (0.51) | MEN1KMT2ALMNAKDM4EALOX5 | |
| SCHEMBL29249036 | 0.71 | MEN1 (0.48) | PDE5AMEN1KMT2ATP53LMNA | |
| SCHEMBL29249055 | 0.69 | MEN1 (0.52) | MEN1KMT2AACHELMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | VELTEN ROBERT | 2008-05-15 | — | — | US | disclosed |
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | VELTEN ROBERT | 2008-05-15 | — | — | US | disclosed |
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | VELTEN ROBERT | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113994-A1 | Annelated Quinoline Derivatives As Pesticide | DDT, ACHE, SIRT4 | PDE1A 257/4885PDE1B 250/4885PDE3B 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.